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Migraines are a common medical condition among youth and adults, affecting 12 percent of people ages 12 and older. They can be especially debilitating in teenagers and often disrupt everyday activities, such as school, music and sports. The innovative treatment -- sphenopalatine ganglion (SPG) block -- does not involve needles touching the patient. Instead, a small flexible catheter is inserted into each nostril and local anesthetic is administered to the SPG, a nerve bundle thought to be associated with migraines, located at the back of the nose. Briefly disabling the SPG can disrupt and reset the headache circuit, breaking a cycle of severe migraines and reducing the need for medication. The minimally invasive SPG block takes almost immediate effect with relief potentially lasting for months, researchers said. SPG blocks are not a frontline treatment. A child only qualifies for the therapy if he/she has been diagnosed with a severe migraine that has not responded to first-line trea...

A getaway to the southern sunshine should be a treat but according to a study done at Aalborg University last year, for one out of twelve people a flight means a severe headache. Now, the same research group is the first in the world to investigate the cause of the problem, and they have a preliminary explanation. "The major changes in cabin pressure at take-off and landing may cause tissue damage and inflammation in the sinuses. This releases the substance PGE2, which can make the blood vessels in the brain expand and thus cause head pain ," says Master's student Sebastian Bao Dinh Bui. Torben Petersen and Sebastian Bao Dinh Bui conducted the study as part of their studies in Medicine with Industrial Specialization (MedIS) at Aalborg University along with their supervisor, Parisa Gazerani, Associate Professor. The group's results have just been published in  The Journal of Headache and Pain. Tests in flight simulator The two Master's students put subjec...

The study, published this month in the journal  Headache , pinpointed a number of possible factors linking migraine and generalized anxiety disorders. First author Professor Esme Fuller-Thomson, Sandra Rotman Endowed Chair at University of Toronto's Factor-Inwentash Faculty of Social Work and Director of the Institute for Life Course & Aging explains, "this link between migraine and generalized anxiety disorders in the past year was partially explained by the disturbingly high prevalence of debilitating chronic pain (30%) and problems in managing household responsibilities (28%) among those with migraine." Co-author and recent MSW graduate from the University of Toronto, Janany Jayanthikumar added, "we were not surprised that chronic pain played a strong role in the link between migraines and generalized anxiety disorders. The unpredictable and uncontrollable nature of migraine pain can be extremely anxiety producing as it often interferes with family and wor...

Outfitted with a joystick and particular glasses, Assistant Professor Alex DaSilva examines 3D pictures of the mind to higher perceive mind chemical fluctuations throughout a migraine headache. DaSilva is within the Michigan Immersive Digital Expertise Nexus, or MIDEN, on North Campus. Credit score: Scott Soderberg, Michigan Images Utilizing PET scans of the mind, College of Michigan researchers confirmed that dopamine falls and fluctuates at completely different occasions throughout a migraine headache. This might assist scientists higher perceive dopamine-based therapies for migraines in addition to a affected person's conduct throughout an assault. The connection between dopamine and migraines has lengthy been a poorly understood therapeutic and analysis space, says Alex DaSilva , assistant professor on the U-M Faculty of Dentistry and Middle for Human Progress and Growth on the College of Michigan. Dopamine -- typically re...

The researchers looked at all available studies on body mass index (BMI) and migraine. "As obesity and being underweight are potentially modifiable risk factors for migraine, awareness of these risk factors is vital for both people with migraine and doctors," said study author B. Lee Peterlin, DO, of Johns Hopkins University School of Medicine and a member of the American Academy of Neurology. "More research is needed to determine whether efforts to help people lose or gain weight could lower their risk for migraine." A total of 12 studies with 288,981 participants were included in the meta-analysis. When the researchers compiled all of the results and adjusted for age and sex , they found that obese people were 27 percent more likely to have migraine than people of normal weight. People who were underweight were 13 percent more likely to have migraine than people of normal weight. Obesity was defined as a BMI of 30 or higher. Underweight was defined as a BMI...

The current research in Helsinki is the primary to look at the consequences of SRI publicity straight on the mind exercise of newborns. The research design aimed toward distinguishing drug-related developmental results from postnatal, environmental results, reminiscent of potential adjustments within the mother-baby relationship because of maternal melancholy. Credit score: S Vanhatalo / Univ. of Helsinki In accordance a brand new research, fetal publicity to generally used SRI medicine might have an effect on mind exercise in newborns. The researchers recommend that the consequences of medication on fetal mind perform ought to be assessed extra rigorously , Indications for preventive medicine ought to be critically evaluated, and non-pharmacological interventions ought to be the first-line therapy for melancholy and anxiousness throughout being pregnant. "We discovered many adjustments within the mind exercise of SRI-exposed ...